Based on the strip quality problem which is seriously affected by the uneven wear of work rolls, this paper analyzes the the work rolls’ uneven wear of F3 and F4 stand, and points out the necessity of using high speed steel rolls. A lot of tests and reaserch have been carried out on the use of high speed steel rolls, while the roll force, roll temperature and oxide film have been analyzed according to the actual data. The process of using high speed steel rolls has been formulated on the basis of a large number of field tests in MaSteel CSP, and it achieves long-term stability of using process conditions. Through the effects of using high speed steel rolls, it has greatly improved the work rolls’ uneven wear and the strip quality.